Blue and Green can struggle to unconditionally remove opponents Creatures, outside of effects like Beast Within and Pongify so Simic decks may appreciate having this card in their arsenal
All of a sudden, a deck could aggressively mill the opponent
If you want to increase your odds, try it in Krark, the Thumbless, or maybe the new Storm, Force of Nature, to get multiple copies of it
#1: Mana Drain Mana Drain is a strong contender for the best counterspell Wizards has ever produced, and its hugely inflated price tag is a testament to that power
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A creature with menace can't be blocked except by two or more creatures