If a replacement effect allows a player to modify or replace an event by untapping a creature that can't become untapped due to the effect of Spider-Woman's last ability, that player may apply that replacement effect, but the creature won't untap
During the opponents turn, when Shanks is rested, all their Characters will have a -1,000 Power reduction, making it harder for the opponent to get attacks through
Django Wexler (August 7, 2019), The Gathering Storm , Chapter Nine
Some build around them while others just benefit from getting extra mana in play
Both modes are nice, but forcing an opponent to attack you can be game-winning
The risk lies in "collector fatigue," where the constant release of new "rarest ever" versions may dilute the prestige of previous serialized runs